Side Effect Management



The most common side effect of AFINITOR® (everolimus) Tablets or AFINITOR DISPERZ® (everolimus tablets for oral suspension) in treating patients with TSC-associated SEGA is mouth sores (also called ulcers).

  • These occur in 62% of patients taking AFINITOR or AFINITOR DISPERZ

Below are tips that you and your doctor may consider to manage mouth sores. If you have a young child, some of these tips might not be appropriate; ask your doctor for guidance.

  1. Banana

    Eat soft foods such as milkshakes, smoothies, pudding, yogurt, mashed potatoes, or bananas.

  2. Tooth

    Take good care of your mouth, and visit your dentist regularly.

  3. Floss

    Floss regularly.

  4. Rinse

    Rinse your mouth several times a day with a mixture of table salt and water.

  5. Doctor

    Check with a doctor, nurse, or pharmacist before using a store-bought mouthwash.

  6. Toothbrush

    Try to brush after every meal with a soft-bristled toothbrush and mild toothpaste.

  1. Grapefruit

    Don’t consume food and drinks that can irritate your mouth (such as citrus fruits and juices, tomatoes, spicy or salty foods, raw ginger, onions, and crunchy chips). 

  2. Alcohol

    Don’t use a mouthwash that contains alcohol, hydrogen peroxide, iodine, or thyme because it may irritate your mouth.

  3. Coffee

    Don’t drink hot liquids.

  4. Allergy

    Don’t eat foods that you are allergic to, and keep in mind any dietary restrictions you may have.

Talk to your doctor right away if you have any questions or concerns.