Side Effect Management

AFINITOR® (everolimus) Tablets


The most common side effect of AFINITOR® (everolimus) Tablets in treating patients with TSC-associated renal angiomyolipomas is mouth sores (also called ulcers). Your doctor may refer to this as stomatitis.

  • These occur in up to 78% of patients taking AFINITOR 
  • Before starting treatment, and during treatment, your doctor may offer some suggestions about proper oral care and what foods to avoid

Below are tips that you and your doctor may consider to manage mouth sores. Ask your doctor which of these suggestions are appropriate for young children.

  1. banana

    Eat soft foods such as milkshakes, smoothies, pudding, yogurt, mashed potatoes, or bananas.

  2. tooth

    Take good care of your mouth, and visit your dentist regularly.

  3. floss

    Floss regularly.

  4. rinse

    Rinse your mouth several times a day with a mixture of table salt and water.

  5. doctor

    Check with a doctor, nurse, or pharmacist before using a store-bought mouthwash.

  6. tooth brush

    Try to brush after every meal with a soft-bristled toothbrush and mild toothpaste.

  1. Grapefruit

    Don’t consume food and drinks that can irritate your mouth (such as citrus fruits and juices, tomatoes, spicy or salty foods, raw ginger, onions, and crunchy chips).

  2. Alcohol

    Don’t use a mouthwash that contains alcohol, hydrogen peroxide, iodine, or thyme because it may irritate your mouth.

  3. Coffee

    Don’t drink hot liquids.

  4. Allergy

    Don’t eat foods that you are allergic to, and keep in mind any dietary restrictions you may have.

Talk to your doctor right away if you have any questions or concerns. Your doctor or nurse may also provide you with a prescription for alcohol-free dexamethasone oral solution to help treat mouth sores.