For US residents only.

Understanding Treatment

AFINITOR Tablets

AFINITOR: A NONSURGICAL TREATMENT FOR TSC-RELATED KIDNEY TUMORS*

*For appropriate patients.

 

AFINITOR® (everolimus) Tablets is a prescription medicine used to treat adults with a kidney tumor called angiomyolipoma, seen with a genetic condition called tuberous sclerosis complex (TSC), when their kidney tumor does not require surgery right away.

 

UNDERSTANDING TSC

TSC is a genetic disease, which means that a gene inside the cells of a person with TSC does not function properly.

  • In people with TSC, there is a defect on one of two genes, either TSC1 (also called hamartin) or TSC2 (also called tuberin) 

  • The defects on these genes prevent them from producing certain proteins that control mTOR

    • mTOR is a pathway that regulates the amount and size of cells