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Side Effect Management 


Working With Your Doctor to Manage Side Effects

If you are taking AFINITOR® (everolimus) Tablets, it is important to tell your health care provider if you have any side effects that bother you or do not go away. Your doctor will monitor you throughout your treatment and can help you determine how to address any side effects you may experience. Your health care provider may change your dose or tell you to interrupt your dose temporarily until symptoms get better or to stop taking AFINITOR.

Management of Mouth Sores When Starting AFINITOR

Mouth sores are the most common side effect of AFINITOR. They can appear as early as within 8 weeks of treatment or at any time during treatment. When you start treatment with AFINITOR, your doctor may prescribe alcohol-free dexamethasone oral solution to reduce the likelihood of getting mouth ulcers or sores and to reduce their severity. Follow your health care provider’s instructions on how to use this prescription mouthwash. If you develop pain, discomfort, or open sores in your mouth, tell your health care provider. Your health care provider may tell you to restart this mouthwash or to use a special mouthwash or mouth gel that does not contain alcohol, peroxide, iodine, or thyme.

FREE 8-Week Supply of Alcohol-Free Dexamethasone Oral Solution

Terms and Conditions

The voucher is good for one 8-week supply of alcohol-free dexamethasone solution 0.5 mg/5 mL (1 bottle = 240 mL), or dexamethasone solution 0.5 mg/5 mL (1 bottle = 500 mL). This free trial is not health insurance. Void where prohibited by law. No purchase required. Prescriber ID# required on prescription. It is illegal for any person to sell, purchase, or trade; or offer to sell, purchase, or trade; or to counterfeit this voucher. Claim shall not be submitted to any public or private third-party payer of any federal or state health care program for reimbursement. Valid only in the United States and Puerto Rico. Offer not valid if reproduced or submitted to any other payer. 


Always follow your doctor’s instructions, and contact your doctor or nurse if you are having any problems.

Dexamethasone Doctor Discussion Guide

Use these topics to help guide a discussion about alcohol-free dexamethasone oral solution with your doctor.

  • Confirm the amount of alcohol-free dexamethasone oral solution your doctor has prescribed
  • Record the length of time your doctor has told you to swish the solution in your mouth
  • Ask your doctor about any food or drink restrictions that are related to your alcohol-free dexamethasone oral solution
  • Note how many times your doctor wants you to use the solution each day

Some Other Oral Care Tips Your Doctor Might Recommend

Things to Do

  • Eat soft foods (such as milkshakes, smoothies, pudding, yogurt, mashed potatoes, or bananas)
  • Take good care of your mouth and visit your dentist regularly
  • Try to brush after every meal with a soft-bristled toothbrush and mild toothpaste
  • Rinse your mouth several times a day with a saltwater mixture
  • If you’re flossing with dental floss, continue with your daily flossing routine. If you have not been flossing daily, do not start, because your mouth may become more sensitive
  • Check with a doctor, nurse, or pharmacist before using a store-bought mouthwash


Things to Avoid

  • Foods and drinks that can irritate your mouth (such as citrus fruits and juices, tomatoes, spicy or salty foods, raw ginger, onions, and crunchy chips)
  • Mouthwash that contains alcohol, hydrogen peroxide, iodine, or thyme, because it may irritate your mouth
  • Drinking hot liquids or beverages
  • Eating foods to which you are allergic
  • Also, keep in mind any dietary restrictions you may have


Discuss Any Side Effects You’re Having

  • It is important that you report any side effects you’re having as soon as possible to your doctor or nurse
  • Your doctor may change your dose of AFINITOR or tell you to temporarily stop treatment if needed
  • Flexible dosing can be a normal part of treatment, and it helps your doctor find the dose of AFINITOR that’s right for you
  • You should not change or adjust your dose by yourself
  • Always follow your doctor’s instructions, and call your doctor or nurse if you are having any problems